Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 18/20 | 0.62 |
| ▸ | CDK4 | P11802 | 12/20 | 0.62 |
| ▸ | CCND1 | P24385 | 9/20 | 0.62 |
| ▸ | CDK1 | P06493 | 3/20 | 0.48 |
| ▸ | CCND3 | P30281 | 3/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231679 | 0.89 | CDK6 (0.63) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19209824 | 0.89 | CDK6 (0.51) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19209882 | 0.89 | CDK6 (0.65) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19209858 | 0.87 | CDK6 (0.73) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19231686 | 0.87 | CDK6 (0.64) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19209843 | 0.86 | CDK6 (0.81) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19231683 | 0.85 | CDK6 (0.64) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19231680 | 0.85 | CDK6 (0.64) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19209860 | 0.85 | CDK6 (0.63) | CDK6CDK4CCND1CDK1CCND3 | |
| SCHEMBL19209797 | 0.85 | CDK6 (0.60) | CDK6CDK4CCND1CDK1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133701-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-08-10 | — | — | WO | claimed |