Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL15822102 | 0.91 | F2 (0.48) | PIN1ALDH1A1TSHRF2F12 | |
| SCHEMBL2475968 | 0.89 | PIN1 (0.58) | PIN1KCNQ2TRPM8IDO1 | |
| SCHEMBL29528570 | 0.89 | PIN1 (0.58) | PIN1KCNQ2TRPM8IDO1 | |
| SCHEMBL176930 | 0.89 | PIN1 (0.58) | PIN1KCNQ2TRPM8IDO1 | |
| SCHEMBL643577 | 0.89 | PIN1 (0.58) | PIN1KCNQ2TRPM8IDO1 | |
| Pyrazole SCHEMBL15375628 | 0.80 | PIN1 (0.45) | PIN1CYP19A1CYP11B2ANO1KCNQ2 | |
| SCHEMBL177082 | 0.79 | IDO1 (0.50) | PIN1ALDH1A1TSHRF2F12 | |
| SCHEMBL29934643 | 0.79 | IDO1 (0.50) | PIN1ALDH1A1TSHRF2F12 | |
| SCHEMBL30252198 | 0.79 | IDO1 (0.50) | PIN1ALDH1A1TSHRF2F12 | |
| SCHEMBL3812210 | 0.79 | IDO1 (0.50) | PIN1ALDH1A1TSHRF2F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411354-A1 | METHOD FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2018-12-12 | — | — | EP | disclosed |
| CN-108602754-A | Process for preparing substituted 4-aminoindane derivatives | 拜耳作物科学股份公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-104995171-B | Difluoromethyl-nicotinic-indanyl carboxamides as fungicides | 拜耳作物科学股份公司 | 2018-02-06 | — | — | CN | disclosed |
| WO-2017133981-A1 | METHOD FOR PRODUCING SUBSTITUTED 4-AMINOINDANE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-10 | — | — | WO | disclosed |
| CN-106795115-A | Difluoromethyl nicotine indanyl formamide | 拜耳作物科学股份公司 | 2017-05-31 | — | — | CN | disclosed |