SCHEMBL1921

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2153	0.88	CYP1A2 (0.41)	BRD4EDNRBEDNRACYP1A2CYP3A4
	SCHEMBL18597726	0.86	POLB (0.51)	BRD4EDNRBEDNRAMEN1KMT2A
	SCHEMBL4359	0.83	EDNRB (0.37)	BRD4EDNRBEDNRACYP1A2CYP3A4
	SCHEMBL3982046	0.83	ALDH1A1 (0.46)	BRD4EDNRBEDNRAMEN1KMT2A
	SCHEMBL14840672	0.81	BRD4 (0.39)	BRD4MEN1KMT2AMAPTKDM4E
	SCHEMBL2984509	0.80	MAPT (0.47)	BRD4MEN1KMT2AMAPTKDM4E
	SCHEMBL5445	0.79	TDP1 (0.41)	EDNRBEDNRACYP1A2CYP3A4CYP2C9
	SCHEMBL18746108	0.78	CYP1A2 (0.40)	BRD4EDNRBEDNRACYP1A2CYP3A4
	SCHEMBL22496040	0.78	PREP (0.45)	BRD4MEN1KMT2AMAPTKDM4E
	SCHEMBL1173	0.77	CYP1A2 (0.39)	BRD4EDNRBEDNRACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.