Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 19/20 | 0.69 |
| ▸ | GRIN2B | Q13224 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219620 | 0.82 | RXRA (1.00) | RXRAGRIN1GRIN2B | |
| SCHEMBL19219271 | 0.80 | RXRA (0.66) | RXRAGRIN1GRIN2B | |
| SCHEMBL19211310 | 0.79 | RXRA (0.75) | RXRAGRIN1GRIN2B | |
| SCHEMBL19211371 | 0.78 | GRIN1 (0.75) | RXRAGRIN1GRIN2B | |
| SCHEMBL19219294 | 0.77 | RXRA (1.00) | RXRAGRIN1GRIN2B | |
| SCHEMBL19219260 | 0.73 | RXRA (1.00) | RXRAGRIN1GRIN2B | |
| SCHEMBL19219496 | 0.73 | RXRA (1.00) | RXRAGRIN1GRIN2B | |
| SCHEMBL19219262 | 0.72 | RXRA (1.00) | RXRAGRIN1GRIN2B | |
| SCHEMBL19219545 | 0.72 | RXRA (1.00) | RXRAGRIN1GRIN2B | |
| SCHEMBL19219163 | 0.71 | RXRA (1.00) | RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414233-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | Janssen Pharmaceutica NV (BE) | 2018-12-19 | — | — | EP | claimed |
| WO-2017139428-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-17 | — | — | WO | claimed |