Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14809383 | 0.85 | FFAR4 (0.44) | KDM4AKDM4CKDM2APLA2G10 | |
| SCHEMBL5509949 | 0.78 | GABRP (0.48) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL9540347 | 0.78 | CYP1A2 (0.48) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL7312929 | 0.78 | CYP1A2 (0.58) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL1437835 | 0.78 | CYP1A2 (0.58) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL11685830 | 0.78 | CYP1A2 (0.48) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL13726724 | 0.77 | TET2 (0.57) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL7343378 | 0.76 | FOLH1 (0.42) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL28304232 | 0.76 | FOLH1 (0.42) | CYP1A2FOLH1GABRPGABRDGABRA1 | |
| SCHEMBL21423297 | 0.76 | FOLH1 (0.54) | CYP1A2FOLH1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414288-A1 | COALESCENTS | Chemoxy International Limited (GB) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137734-A1 | COALESCENTS | CHEMOXY INTERNATIONAL LIMITED (GB) | 2017-08-17 | — | — | WO | disclosed |