Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.44 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467719 | 0.90 | KMT2A (0.53) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL1467723 | 0.90 | KMT2A (0.53) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL17185074 | 0.90 | KMT2A (0.53) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL1467721 | 0.90 | KMT2A (0.53) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL3187533 | 0.88 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL7835003 | 0.88 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL19121559 | 0.88 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL7834998 | 0.88 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL3187519 | 0.88 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE | |
| SCHEMBL1781856 | 0.88 | KMT2A (0.55) | KMT2AL3MBTL1NPFFR1NPFFR2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414252-A1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | Forma Therapeutics, Inc. (US) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017139778-A1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2017-08-17 | — | — | WO | disclosed |