Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 2/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.44 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467721 | 0.91 | KMT2A (0.53) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL1467723 | 0.91 | KMT2A (0.53) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL1467719 | 0.91 | KMT2A (0.53) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL19212166 | 0.90 | KMT2A (0.53) | KMT2AL3MBTL1JAK1BCHEKCNA3 | |
| SCHEMBL4372414 | 0.89 | DRD2 (0.56) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL4369305 | 0.89 | DRD2 (0.56) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL4372426 | 0.89 | DRD2 (0.56) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL4369301 | 0.89 | DRD2 (0.56) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL4369297 | 0.89 | DRD2 (0.56) | KMT2AL3MBTL1BCHEKCNA3MEN1 | |
| SCHEMBL2180789 | 0.88 | UBE2M (0.55) | KMT2AL3MBTL1BCHEKCNA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015161011-A1 | BENZAMIDE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |