Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967524 | 0.87 | GSK3A (0.69) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL9941874 | 0.87 | GSK3A (0.69) | GSK3AGSK3BJAK2SRCFLT3 | |
| SCHEMBL19944279 | 0.86 | GSK3A (0.48) | GSK3AGSK3B | |
| SCHEMBL21117553 | 0.86 | GSK3A (0.48) | GSK3AGSK3B | |
| SCHEMBL19944288 | 0.86 | GSK3A (0.48) | GSK3AGSK3B | |
| SCHEMBL19944284 | 0.85 | GSK3A (0.47) | GSK3AGSK3B | |
| SCHEMBL21117461 | 0.85 | GSK3A (0.47) | GSK3AGSK3B | |
| SCHEMBL19944287 | 0.85 | GSK3A (0.47) | GSK3AGSK3B | |
| SCHEMBL21117455 | 0.84 | GSK3A (0.43) | GSK3AGSK3B | |
| SCHEMBL19944206 | 0.84 | GSK3A (0.43) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597390-B2 | Indoles for use in influenza virus infection | JANSSEN SCIENCES IRELAND UC (IE) | 2020-03-24 | — | — | US | disclosed |
| US-20170226102-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN INFECTIOUS DISEASES BVBA (BE) | 2017-08-10 | — | — | US | disclosed |
| US-20170226102-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN INFECTIOUS DISEASES BVBA (BE) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597390-B2 | Indoles for use in influenza virus infection | IDO1, IDO2, INMT | GSK3A 131/4885GSK3B 89/4885JAK2 457/4885 |
| US-20170226102-A1 | INDOLES FOR USE IN INFLUENZA VIRUS INFECTION | IDO1, IDO2, INMT | GSK3A 131/4885GSK3B 89/4885JAK2 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.