SCHEMBL1921439

SCHEMBL1921439

[NH]c1ccc2ccccc2c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
WDR5 P61964 1/20 0.44
HPRT1 P00492 1/20 0.42
MAPT P10636 4/20 0.41
ESR1 P03372 5/20 0.40
ESR2 Q92731 5/20 0.40
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
LMNA P02545 3/20 0.39
NPC1 O15118 1/20 0.39
RECQL P46063 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DNMT1 P26358 1/20 0.38
ALOX5 P09917 1/20 0.38
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014875 0.86 CYP2A6 (0.55) ALDH1A1HSD17B10TDP1CYP2A6TSHR
Phenanthrene SCHEMBL28355895 0.76 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL191449 0.76 DNMT1 (0.48) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL30034855 0.76 DNMT1 (0.48) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL28896074 0.76 ALDH1A1 (0.48) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL6310656 0.74 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1CYP2A6TSHR
Ammonia Solution, Strong SCHEMBL12818906 0.74 DNMT1 (0.47) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL12695622 0.74 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL619730 0.74 ESR1 (0.61) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL3153755 0.74 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed