Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.76 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.76 |
| ▸ | F10 | P00742 | 5/20 | 0.61 |
| ▸ | PLAT | P00750 | 4/20 | 0.61 |
| ▸ | PLG | P00747 | 4/20 | 0.56 |
| ▸ | PROC | P04070 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | F9 | P00740 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197983 | 0.92 | F11 (0.80) | F11KLKB1F10PLATPLG | |
| SCHEMBL1197986 | 0.92 | F11 (0.80) | F11KLKB1F10PLATPLG | |
| SCHEMBL1196877 | 0.90 | F11 (0.77) | F11KLKB1F10PLATPLG | |
| SCHEMBL1196878 | 0.90 | F11 (0.77) | F11KLKB1F10PLATPLG | |
| SCHEMBL1920923 | 0.89 | F11 (0.78) | F11KLKB1F10PLATPLG | |
| SCHEMBL1197670 | 0.87 | F11 (0.84) | F11KLKB1F10PLATPLG | |
| SCHEMBL1197674 | 0.87 | F11 (0.84) | F11KLKB1F10PLATPLG | |
| SCHEMBL1197821 | 0.86 | F11 (0.79) | F11KLKB1F10PLATPLG | |
| SCHEMBL1197826 | 0.86 | F11 (0.79) | F11KLKB1F10PLATPLG | |
| SCHEMBL1197929 | 0.86 | F11 (1.00) | F11KLKB1F10PLATPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-B1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-01 | — | — | EP | claimed |