SCHEMBL19214635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19214634	0.90	EGFR (0.51)	MAPTLMNAEGFRHDAC3HDAC1
	SCHEMBL28791746	0.89	HDAC3 (0.52)	MAPTLMNASMN1; SMN2EGFRHDAC3
	SCHEMBL19214633	0.89	MAPT (0.54)	MAPTLMNASMN1; SMN2EGFRHDAC3
	SCHEMBL1683696	0.83	HDAC3 (0.67)	MAPTEGFRHDAC3HDAC1HDAC7
	SCHEMBL786841	0.78	EGFR (0.48)	MAPTEGFRHDAC3HDAC1HDAC7
	SCHEMBL721855	0.78	HDAC3 (0.54)	EGFRHDAC3HDAC1HDAC7HDAC8
	Hydrochloric Acid SCHEMBL721844	0.77	HDAC3 (0.53)	EGFRHDAC3HDAC1HDAC7HDAC8
	SCHEMBL1683830	0.75	HDAC3 (0.67)	EGFRHDAC3HDAC1HDAC7HDAC8
	SCHEMBL18081569	0.75	HDAC3 (0.66)	EGFRHDAC3HDAC1HDAC7HDAC8
	SCHEMBL722723	0.74	HDAC3 (0.66)	EGFRHDAC3HDAC1HDAC7HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.