Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28791746 | 0.91 | HDAC3 (0.52) | MAPTALDH1A1LMNAECE1SMN1; SMN2 | |
| SCHEMBL19214634 | 0.90 | EGFR (0.51) | MAPTLMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL19214635 | 0.89 | MAPT (0.55) | MAPTLMNARAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL20850974 | 0.82 | HDAC3 (0.67) | HDAC1HDAC8HDAC6EGFRHDAC3 | |
| SCHEMBL723752 | 0.82 | HDAC3 (0.67) | HDAC1HDAC8HDAC6EGFRHDAC3 | |
| SCHEMBL1683730 | 0.77 | EGFR (0.60) | HDAC1HDAC8HDAC6EGFRHDAC3 | |
| SCHEMBL721918 | 0.77 | HPGDS (0.54) | HDAC1HDAC8HDAC6HDAC3HDAC7 | |
| SCHEMBL786801 | 0.77 | EGFR (0.49) | HDAC1HDAC8HDAC6EGFRHDAC3 | |
| SCHEMBL786549 | 0.76 | HDAC3 (0.63) | HDAC1HDAC8HDAC6EGFRHDAC3 | |
| Hydrochloric Acid SCHEMBL771834 | 0.76 | HPGDS (0.53) | HDAC1HDAC8HDAC6HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170226086-A1 | COMPOUNDS FOR TREATMENT OF CANCER | GTx. Inc. (US) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226086-A1 | COMPOUNDS FOR TREATMENT OF CANCER | KLK3, BRDT, ACP3 | MAPT 2614/4885ALDH1A1 209/4885LMNA 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.