Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025396 | 0.74 | MASP2 (0.35) | — | |
| SCHEMBL20365914 | 0.70 | MAPT (0.41) | ERBB2MAPTAGTR1PIK3CGHTT | |
| SCHEMBL12410800 | 0.65 | — | — | |
| SCHEMBL23913820 | 0.64 | MAPT (0.36) | ERBB2MAPTAGTR1HTT | |
| SCHEMBL22173878 | 0.64 | MAPT (0.36) | ERBB2MAPTAGTR1HTT | |
| SCHEMBL12141955 | 0.64 | PIK3CG (0.39) | ERBB2MAPTAGTR1PIK3CGHTT | |
| SCHEMBL21075865 | 0.61 | ERBB2 (0.39) | ERBB2MAPTAGTR1 | |
| SCHEMBL17133135 | 0.61 | KDM5A (0.37) | ERBB2PIK3CGHTT | |
| SCHEMBL22844983 | 0.60 | KDM5A (0.36) | MAPTAGTR1HTT | |
| SCHEMBL10149763 | 0.58 | MAPT (0.36) | MAPTAGTR1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725442-B2 | Heterocyclic derivative having PGD2 receptor antagonist activity | SHIONOGI & CO., LTD. (JP) | 2017-08-08 | — | — | US | disclosed |