SCHEMBL19215316

SCHEMBL19215316

CCCC/C=C/CC(Cl)CCC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
FAAH O00519 4/20 0.35
TRPV1 Q8NER1 2/20 0.35
F7 P08709 1/20 0.35
F3 P13726 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
ALDH1A1 P00352 2/20 0.34
LTB4R Q15722 2/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
TSHR P16473 2/20 0.32
LPAR2 Q9HBW0 2/20 0.32
LPAR3 Q9UBY5 2/20 0.32
PPARA Q07869 1/20 0.32
LPAR1 Q92633 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764481 0.80 TSHR (0.33) ALDH1A1TSHR
SCHEMBL19458652 0.77 FFAR1 (0.35) FFAR1FFAR4FAAHTRPV1
SCHEMBL23628565 0.76 PPARG (0.42) FFAR1FFAR4FAAHALDH1A1TSHR
SCHEMBL2002722 0.76 FFAR1 (0.38) FFAR1FFAR4FAAHTRPV1F7
SCHEMBL2002721 0.76 FFAR1 (0.38) FFAR1FFAR4FAAHTRPV1F7
SCHEMBL8764482 0.72 TSHR (0.38) FFAR1FFAR4FAAHTRPV1ALDH1A1
SCHEMBL16276203 0.72 FFAR1 (0.30) FFAR1FFAR4
SCHEMBL17262056 0.72 FAAH (0.55) FAAHTRPV1F7F3ALDH1A1
SCHEMBL93117 0.72 FAAH (0.55) FAAHTRPV1F7F3ALDH1A1
SCHEMBL23566850 0.72 FAAH (0.55) FAAHTRPV1F7F3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2493457-B1 FAST DISSOLVING SOLID DOSAGE FORM IX BIOPHARMA LTD (SG) 2017-08-09 EP disclosed