SCHEMBL19215817

SCHEMBL19215817

Cc1ccc(N=Nc2ccc(OC(=O)C(CC(C)C)C(C)C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 2/20 0.42
▸ NPC1 O15118 4/20 0.41
▸ MAPT P10636 4/20 0.41
▸ RAB9A P51151 4/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ MAPK1 P28482 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41
▸ KMT2A Q03164 3/20 0.40
▸ LMNA P02545 2/20 0.40
▸ PRSS1 P07477 2/20 0.39
▸ ACR P10323 2/20 0.39
▸ PPARD Q03181 1/20 0.38
▸ PPARA Q07869 1/20 0.38
▸ ALDH1A1 P00352 4/20 0.36
▸ GAA P10253 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ CES2 O00748 1/20 0.35
▸ ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25522011 0.91 LMNA (0.47) ELANEKMT2ALMNAALDH1A1GAA
SCHEMBL19867625 0.84 GSK3B (0.41) ELANENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL19215818 0.84 PPARD (0.42) ELANEMAPTPRSS1ACRPPARD
SCHEMBL21291493 0.79 ELANE (0.42) ELANEMAPTSMN1; SMN2MAPK1LMNA
SCHEMBL17131758 0.78 ELANE (0.45) ELANENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL19573301 0.77 ATM (0.50) ELANENPC1MAPTRAB9AMAPK1
SCHEMBL18512374 0.77 ELANE (0.46) ELANENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL19851398 0.74 POLB (0.39) ELANEMAPTTDP1KMT2ALMNA
SCHEMBL19118004 0.72 ELANE (0.36) ELANENPC1MAPTRAB9AMAPK1
SCHEMBL11964668 0.72 LMNA (0.77) ELANENPC1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190235134-A1 ANTIREFLECTION FILM, POLARIZING PLATE, IMAGE DISPLAY DEVICE, ANTIREFLECTION PRODUCT, METHOD OF MANUFACTURING LAMINATE, AND METHOD OF MANUFACTURING ANTIREFLECTION FILM FUJIFILM CORPORATION (JP) 2019-08-01 — — US disclosed
US-9726798-B2 Optical film, polarizing plate, and method for producing optical film FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
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