Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19540793 | 0.83 | IDH1 (0.48) | IDH1 | |
| SCHEMBL19216845 | 0.80 | HTR1B (0.46) | IDH1 | |
| SCHEMBL19540794 | 0.80 | IDH1 (0.48) | IDH1 | |
| SCHEMBL3697186 | 0.71 | MAOB (0.50) | RXRA | |
| SCHEMBL3697185 | 0.71 | MAOB (0.50) | RXRA | |
| SCHEMBL9179498 | 0.71 | MAOB (0.50) | RXRA | |
| SCHEMBL6785056 | 0.66 | RXRA (0.55) | RXRA | |
| SCHEMBL6785053 | 0.66 | RXRA (0.55) | RXRA | |
| SCHEMBL6785050 | 0.66 | RXRA (0.55) | RXRA | |
| Hydrochloric Acid SCHEMBL6785658 | 0.65 | RXRA (0.54) | RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202766-A1 | ISOXAZOLE DERIVATIVE AS MUTATED ISOCITRATE DEHYDROGENASE 1 INHIBITOR | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-08-09 | — | — | EP | disclosed |