Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | MPC2 | O95563 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21504707 | 0.88 | FFAR1 (0.44) | FFAR1PPARGCYP3A4RXRAPPARA | |
| SCHEMBL24050797 | 0.84 | PPARG (0.57) | PPARGMPC2CYP2C8CYP2C9RAB9A | |
| SCHEMBL21504810 | 0.83 | PPARG (0.56) | FFAR1PPARGCYP3A4MPC2CYP2C8 | |
| SCHEMBL21504808 | 0.83 | PPARG (0.56) | FFAR1PPARGCYP3A4MPC2CYP2C8 | |
| SCHEMBL19217598 | 0.81 | MAOB (0.41) | FFAR1PPARGCYP3A4RXRAPPARA | |
| SCHEMBL6931816 | 0.80 | FFAR1 (0.66) | FFAR1PPARGCYP3A4RXRAMPC2 | |
| SCHEMBL19217637 | 0.80 | PPARG (0.70) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL21504803 | 0.78 | PPARG (0.71) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL19491786 | 0.77 | PPARG (0.63) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL20158318 | 0.77 | PPARG (0.72) | FFAR1PPARGCYP3A4RXRAMPC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202401-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Octeta Therapeutics, LLC (US) | 2017-08-09 | — | — | EP | disclosed |