Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | MPC2 | O95563 | 2/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21504803 | 0.89 | PPARG (0.71) | PPARGMPC2CYP2C8CYP2C9MAPT | |
| SCHEMBL24943391 | 0.89 | PPARG (0.68) | PPARGMPC2CYP2C8CYP2C9MAPT | |
| SCHEMBL21504834 | 0.86 | PPARG (0.52) | PPARGMPC2CYP2C8CYP2C9MAPT | |
| SCHEMBL19217604 | 0.84 | FFAR1 (0.45) | PPARGMPC2CYP2C8CYP2C9RAB9A | |
| SCHEMBL23836847 | 0.82 | PPARG (0.83) | PPARGMPC2CYP2C8CYP2C9MAPT | |
| SCHEMBL937521 | 0.82 | PPARG (0.83) | PPARGMPC2CYP2C8CYP2C9MAPT | |
| SCHEMBL24050788 | 0.81 | PPARG (0.55) | PPARGMPC2CYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL25833061 | 0.81 | PPARG (0.55) | PPARGMPC2CYP2C8CYP2C9ALDH1A1 | |
| SCHEMBL21504808 | 0.79 | PPARG (0.56) | PPARGMPC2CYP2C8CYP2C9MAPT | |
| SCHEMBL21504810 | 0.79 | PPARG (0.56) | PPARGMPC2CYP2C8CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210361629-A1 | THIAZOLIDINEDIONE ANALOGS FOR THE TREATMENT OF NAFLD AND METABOLIC DISEASES | CIRIUS THERAPEUTICS, INC. | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210361629-A1 | THIAZOLIDINEDIONE ANALOGS FOR THE TREATMENT OF NAFLD AND METABOLIC DISEASES | PPARD, FABP1, GOT2 | PPARG 4/4885MPC2 194/4885CYP2C8 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.