Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.49 |
| ▸ | MPC2 | O95563 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929469 | 0.79 | PPARG (0.70) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6928346 | 0.78 | PPARG (0.57) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL19559734 | 0.76 | PPARG (0.36) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6930599 | 0.75 | PPARG (0.71) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL6930627 | 0.75 | PPARG (0.71) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL6930853 | 0.75 | PPARG (0.71) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL6930274 | 0.75 | FFAR1 (0.56) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL2608677 | 0.71 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL19217579 | 0.71 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL19828508 | 0.71 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202401-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Octeta Therapeutics, LLC (US) | 2017-08-09 | — | — | EP | disclosed |