Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467543 | 0.91 | PTGDR2 (0.47) | PTGDR2PTGDR | |
| SCHEMBL1599839 | 0.91 | PTGDR2 (0.47) | PTGDR2PTGDR | |
| SCHEMBL1466409 | 0.91 | PTGDR2 (0.56) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1603176 | 0.90 | PTGDR2 (0.56) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1467977 | 0.84 | PTGDR2 (0.62) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL3723720 | 0.84 | PTGDR2 (0.52) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL3792480 | 0.84 | PTGDR2 (0.52) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1599312 | 0.83 | PTGDR2 (0.56) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1466412 | 0.83 | PTGDR2 (0.51) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1465815 | 0.82 | PTGDR2 (0.50) | PTGDR2PTGDRPTGIRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327693-A1 | Indoles and their therapeutic use | Pulmagen Therapeutics (Asthma) Limited (GB) | 2011-06-01 | — | — | EP | disclosed |