Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718032 | 0.92 | PTGDR2 (0.44) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1466409 | 0.85 | PTGDR2 (0.56) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1603176 | 0.84 | PTGDR2 (0.56) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1921782 | 0.84 | PTGDR2 (0.57) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL3792480 | 0.84 | PTGDR2 (0.52) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1599312 | 0.81 | PTGDR2 (0.56) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL3714820 | 0.81 | PTGDR2 (0.50) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL1467977 | 0.80 | PTGDR2 (0.62) | PTGDR2PTGDRCYP2C9 | |
| SCHEMBL1422452 | 0.80 | PTGDR2 (0.52) | PTGDR2PTGDRPTGIRCYP2C9 | |
| SCHEMBL3717855 | 0.80 | PTGDR2 (0.52) | PTGDR2PTGDRPTGIRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | claimed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |