Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | MPC2 | O95563 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931098 | 0.83 | PPARG (0.45) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL16491938 | 0.83 | PPARG (0.45) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6929667 | 0.77 | PPARG (0.64) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6928300 | 0.77 | PPARG (0.64) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6930220 | 0.77 | PPARG (0.64) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6930478 | 0.76 | PPARG (0.50) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL14408623 | 0.75 | PPARG (0.50) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL12628859 | 0.75 | PPARG (0.50) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6931166 | 0.75 | PPARG (0.48) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL6931096 | 0.75 | PPARG (0.48) | PPARGMPC2CYP2C8CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202401-A1 | PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Octeta Therapeutics, LLC (US) | 2017-08-09 | — | — | EP | disclosed |