Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 4/20 | 0.49 |
| ▸ | RXRB | P28702 | 3/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982170 | 0.92 | CA1 (0.52) | KMT2AMEN1CYP1A2RXRARXRB | |
| SCHEMBL19217953 | 0.84 | CA12 (0.40) | KMT2AMEN1CYP1A2POLBCA1 | |
| SCHEMBL14627800 | 0.81 | MAPT (0.62) | KMT2AMEN1CYP1A2NPC1POLB | |
| SCHEMBL14533677 | 0.81 | LMNA (0.44) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL13801167 | 0.80 | ELANE (0.53) | ALDH1A1 | |
| SCHEMBL24973109 | 0.80 | MEN1 (0.39) | KMT2AMEN1CYP1A2NPC1POLB | |
| SCHEMBL14473046 | 0.80 | CA1 (0.53) | KMT2ARXRARXRBNR4A2SRD5A2 | |
| SCHEMBL24108828 | 0.80 | ELANE (0.52) | KMT2AMEN1CYP1A2CYP2C9RAB9A | |
| SCHEMBL1634704 | 0.80 | PARP15 (0.58) | KMT2ARXRARXRBNR4A2SRD5A2 | |
| SCHEMBL71433 | 0.79 | SRD5A2 (0.65) | KMT2AMEN1CYP1A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052547-B1 | POLYDIORGANOSILOXANE-POLYCARBONATE BLOCK COPOLYMERS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-08-09 | — | — | EP | disclosed |