Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922048 | 0.90 | F11 (0.53) | F11KLKB1AAK1CYP17A1 | |
| SCHEMBL1196623 | 0.89 | F11 (0.52) | F11KLKB1AAK1CYP17A1 | |
| SCHEMBL1196982 | 0.88 | F11 (0.51) | F11KLKB1AAK1 | |
| SCHEMBL1196979 | 0.88 | F11 (0.51) | F11KLKB1AAK1 | |
| SCHEMBL1197002 | 0.85 | F11 (0.58) | F11KLKB1CYP17A1 | |
| SCHEMBL1196625 | 0.85 | F11 (0.69) | F11KLKB1 | |
| SCHEMBL1197016 | 0.83 | F11 (0.60) | F11KLKB1 | |
| SCHEMBL1195900 | 0.83 | F11 (0.62) | F11KLKB1 | |
| SCHEMBL1195903 | 0.83 | F11 (0.62) | F11KLKB1 | |
| SCHEMBL1197013 | 0.83 | F11 (0.60) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-B1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-01 | — | — | EP | disclosed |