SCHEMBL19221007

SCHEMBL19221007

O=S(=O)(O)CCC1CC2CCCC(C2)C1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
INPP5A Q14642 1/20 0.33
PTGS1 P23219 1/20 0.30
PDE4A P27815 1/20 0.30
LMNA P02545 1/20 0.30
SLC6A6 P31641 1/20 0.30
CYP2C19 P33261 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18799418 0.89 MAPT (0.41) MAPTINPP5A
SCHEMBL19719172 0.87 MAPT (0.41) MAPTINPP5A
SCHEMBL9320849 0.81 PTGS1 (0.36) INPP5APTGS1PDE4ALMNASLC6A6
SCHEMBL21398688 0.78
SCHEMBL18993403 0.78 ALDH1A1 (0.32) MAPT
SCHEMBL4072061 0.76 ALDH1A1 (0.37) INPP5APTGS1PDE4ALMNASLC6A6
SCHEMBL18826744 0.76 MAPT (0.33) MAPT
SCHEMBL8078390 0.75
SCHEMBL6584519 0.74 ALDH1A1 (0.36) INPP5APTGS1PDE4ALMNASLC6A6
SCHEMBL2518041 0.74 HPGD (0.39) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023674-B2 Monomer, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-07-17 US disclosed
US-20170226252-A1 MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023674-B2 Monomer, polymer, resist composition, and patterning process PARG, SMARCA1, SMARCA2 MAPT 1218/4885INPP5A 1060/4885PTGS1 4329/4885
US-20170226252-A1 MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS PARG, SMARCA1, SMARCA2 MAPT 1218/4885INPP5A 1060/4885PTGS1 4329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.