SCHEMBL19221808

SCHEMBL19221808

COC[C@@](CO)(COP(OCCC#N)N(C(C)C)C(C)C)O[C@H](COC(=O)c1ccccc1)n1ccc(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19221888 1.00 POLB (0.46) POLBHSD17B10
SCHEMBL17445607 0.92 POLB (0.47) POLBHSD17B10
SCHEMBL19221812 0.90 POLB (0.42) POLBHSD17B10
SCHEMBL13443476 0.84 POLB (0.52) POLBHSD17B10
SCHEMBL19221785 0.84 POLB (0.30) POLBHSD17B10
SCHEMBL13896530 0.83 POLB (0.47) POLBHSD17B10
SCHEMBL19221806 0.82 POLB (0.63) POLBHSD17B10
SCHEMBL20052008 0.76 POLB (0.52) POLBHSD17B10
SCHEMBL17445606 0.76 POLB (0.62) POLBHSD17B10
SCHEMBL17445609 0.75 POLB (0.30) POLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9725474-B2 Modified nucleic acid TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-08-08 — — US disclosed
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