Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867638 | 0.94 | POLB (0.50) | POLBHSD17B10 | |
| SCHEMBL13896530 | 0.85 | POLB (0.47) | POLBHSD17B10 | |
| SCHEMBL20052002 | 0.81 | POLB (0.32) | POLBHSD17B10ADRB2ADRB1ADRB3 | |
| SCHEMBL13443476 | 0.81 | POLB (0.52) | POLBHSD17B10DUT | |
| SCHEMBL20052005 | 0.80 | POLB (0.72) | POLBHSD17B10ADRB2ADRB1ADRB3 | |
| SCHEMBL17445607 | 0.78 | POLB (0.47) | POLBHSD17B10 | |
| SCHEMBL14867649 | 0.76 | POLB (0.31) | POLBHSD17B10 | |
| SCHEMBL19221808 | 0.76 | POLB (0.46) | POLBHSD17B10 | |
| SCHEMBL19221888 | 0.76 | POLB (0.46) | POLBHSD17B10 | |
| SCHEMBL20052007 | 0.76 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944929-B2 | UNA single stranded oligomers for therapeutics | ARCTURUS THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |