Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.64 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19222881 | 0.81 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL15790619 | 0.78 | CNR2 (0.63) | CNR2CNR1PDE10A | |
| SCHEMBL15776136 | 0.78 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14151962 | 0.78 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL19222911 | 0.72 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL15776261 | 0.71 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL19956438 | 0.67 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL20057372 | 0.67 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL15788897 | 0.67 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14242991 | 0.67 | CNR2 (0.57) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928868-B1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2017-08-09 | — | — | EP | disclosed |