Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102940 | 0.85 | SIGMAR1 (0.50) | SIGMAR1CYP2D6LMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28600382 | 0.83 | SIGMAR1 (0.48) | SIGMAR1CYP2D6LMNACYP1A2CYP3A4 | |
| Water SCHEMBL28622482 | 0.83 | SIGMAR1 (0.48) | SIGMAR1CYP2D6LMNACYP1A2CYP3A4 | |
| SCHEMBL12851500 | 0.83 | ZDHHC7 (0.45) | SMN1; SMN2ZDHHC7MEN1KMT2ACA1 | |
| SCHEMBL6278163 | 0.80 | ZDHHC7 (0.58) | LMNAZDHHC7MEN1KMT2ACA1 | |
| SCHEMBL15710769 | 0.79 | SIGMAR1 (0.42) | SIGMAR1CYP2D6LMNACYP1A2CYP3A4 | |
| SCHEMBL17102902 | 0.79 | TDP1 (0.45) | SIGMAR1CYP2D6LMNACYP1A2CYP3A4 | |
| SCHEMBL25186102 | 0.78 | ZDHHC7 (0.61) | LMNAZDHHC7MEN1KMT2ACA1 | |
| SCHEMBL8816714 | 0.78 | ZDHHC7 (0.61) | LMNAZDHHC7MEN1KMT2ACA1 | |
| SCHEMBL9792556 | 0.78 | ZDHHC7 (0.61) | LMNAZDHHC7MEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | disclosed |