⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12022864 | 0.84 | — | — | |
| SCHEMBL19634486 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL12059199 | 0.77 | — | — | |
| SCHEMBL12039835 | 0.77 | — | — | |
| SCHEMBL25663949 | 0.76 | PIK3CD (0.37) | — | |
| SCHEMBL21659483 | 0.76 | — | — | |
| SCHEMBL25132584 | 0.73 | NUDT1 (0.32) | — | |
| SCHEMBL12039842 | 0.73 | — | — | |
| SCHEMBL14016289 | 0.70 | — | — | |
| SCHEMBL12039750 | 0.70 | PIK3CD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10022454-B2 | Functionalized phosphorodiamites for therapeutic oligonucleotide synthesis | LIPOSCIENCES, LLC (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170224832-A9 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2017-08-10 | — | — | US | disclosed |