Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21603522 | 0.81 | GRIA2 (0.37) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17659028 | 0.78 | MEN1 (0.35) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21603395 | 0.76 | HPGD (0.36) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21603448 | 0.74 | LARS1 (0.33) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3344312 | 0.71 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29362737 | 0.71 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8407148 | 0.71 | KDM4E (0.41) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30329719 | 0.70 | MAPT (0.40) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8525889 | 0.67 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12062654 | 0.67 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202765-A1 | POLYCYCLIC ANAPLASTIC LYMPHOMA KINASE INHIBITOR | Xuanzhu Pharma Co., Ltd. (CN) | 2017-08-09 | — | — | EP | disclosed |