SCHEMBL19225465

SCHEMBL19225465

O=Cc1cc(OCC(F)(F)F)c(C2CC2)cn1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28069002 0.80 CNR2 (0.59) CNR2
SCHEMBL19223929 0.78 CNR2 (0.60) CNR2
SCHEMBL29423350 0.78 CNR2 (0.70) CNR2
SCHEMBL15776331 0.78 CNR2 (0.70) CNR2
SCHEMBL19225483 0.76 CNR2 (0.53) CNR2
SCHEMBL15777951 0.76 CNR2 (0.63) CNR2
SCHEMBL16115426 0.75 CNR2 (0.57) CNR2
SCHEMBL15351763 0.75 ALDH1A1 (0.40) CNR2
SCHEMBL28820933 0.73 CNR2 (0.44) CNR2
SCHEMBL15777205 0.73 CNR2 (0.52) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2928867-B1 PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS HOFFMANN LA ROCHE (CH) 2017-08-09 EP disclosed