Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15574512 | 0.77 | PDE2A (0.31) | S1PR1PDE2AEPHX2 | |
| SCHEMBL3792156 | 0.75 | S1PR4 (0.47) | S1PR4RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL18188355 | 0.74 | S1PR4 (0.38) | S1PR4RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL23044977 | 0.73 | MBOAT4 (0.36) | S1PR1MBOAT4PDE2AEPHX2HSD11B1 | |
| SCHEMBL30932108 | 0.73 | MBOAT4 (0.36) | S1PR1MBOAT4PDE2AEPHX2HSD11B1 | |
| SCHEMBL18149090 | 0.73 | MBOAT4 (0.43) | S1PR4RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL30328684 | 0.73 | CCR1 (0.37) | RAB9ANPC1SMN1; SMN2S1PR1LMNA | |
| SCHEMBL19851263 | 0.73 | MBOAT4 (0.46) | MBOAT4PDE2AGRM2 | |
| SCHEMBL20116703 | 0.71 | S1PR4 (0.55) | S1PR4RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL24156418 | 0.71 | S1PR4 (0.44) | S1PR4RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724351-B2 | Compounds for the treatment of paramoxyvirus viral infections | ALIOS BIOPHARMA, INC. (US) | 2017-08-08 | — | — | US | disclosed |