Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 4/20 | 0.34 |
| ▸ | FAP | Q12884 | 4/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 7/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225946 | 0.86 | CFD (0.40) | CFDPREPFAPKDM4CF2 | |
| SCHEMBL19225818 | 0.84 | CFD (0.42) | CFDKDM4CF2 | |
| SCHEMBL15597267 | 0.83 | CFD (0.39) | CFDPREPFAPKDM4C | |
| SCHEMBL19225826 | 0.83 | CFD (0.43) | CFDPREPFAPKDM4CF2 | |
| SCHEMBL19226032 | 0.83 | CFD (0.44) | CFDPREPFAPKDM4CF2 | |
| SCHEMBL19225822 | 0.82 | CFD (0.40) | CFDPREPKDM4CF2 | |
| SCHEMBL19225959 | 0.82 | CFD (0.40) | CFDKDM4CF2 | |
| SCHEMBL19226053 | 0.82 | CFD (0.41) | CFDPREPFAPKDM4C | |
| SCHEMBL19225835 | 0.81 | CFD (0.42) | CFDPREPFAPKDM4CF2 | |
| SCHEMBL19225960 | 0.81 | CFD (0.43) | CFDFKBP1APREPFAPKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |