⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219806 | 1.00 | — | — | |
| SCHEMBL1122835 | 0.82 | — | — | |
| SCHEMBL30839689 | 0.82 | — | — | |
| SCHEMBL25342001 | 0.73 | — | — | |
| SCHEMBL127816 | 0.71 | — | — | |
| SCHEMBL16291827 | 0.70 | — | — | |
| SCHEMBL383561 | 0.69 | — | — | |
| SCHEMBL1600759 | 0.69 | CRBN (0.30) | — | |
| SCHEMBL9173461 | 0.68 | — | — | |
| SCHEMBL1702925 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |