⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839689 | 0.80 | — | — | |
| SCHEMBL127816 | 0.76 | — | — | |
| SCHEMBL8300820 | 0.76 | — | — | |
| SCHEMBL11010193 | 0.72 | — | — | |
| SCHEMBL27841594 | 0.69 | — | — | |
| SCHEMBL19225955 | 0.69 | — | — | |
| SCHEMBL1219806 | 0.69 | — | — | |
| SCHEMBL28361672 | 0.68 | — | — | |
| SCHEMBL3569228 | 0.68 | — | — | |
| SCHEMBL984927 | 0.67 | CRBN (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112315940-B | Nanoparticle for promoting tumor coagulation and enzyme/ATP dual-responsive drug release, and preparation method and application thereof | 暨南大学 | 2022-12-06 | — | — | CN | claimed |
| CN-112315940-A | Nanoparticle for promoting tumor coagulation and enzyme/ATP dual-responsive drug release, and preparation method and application thereof | 暨南大学 | 2021-02-05 | — | — | CN | claimed |
| CN-105663083-B | Chitosan-based high medicine-carried nano particles of one kind and the preparation method and application thereof | 暨南大学 | 2018-12-14 | — | — | CN | claimed |
| CN-105534957-B | A kind of core-shell structure nanometer particle of reduction/enzyme/pH multiple responses drug release | 暨南大学 | 2018-05-08 | — | — | CN | claimed |
| CN-105534957-A | Core-shell structure nanoparticles for reduction/enzyme/pH multi-responsive drug release | UNIV JINAN | 2016-05-04 | — | — | CN | claimed |
| CN-103784437-A | Application of Hsp90 inhibitor in preparing tumor multi-drug resistance reversal agents | UNIV JINAN | 2014-05-14 | — | — | CN | claimed |
| CN-101481353-B | Tetrahydro indazolone or tetrahydro indolone substituted indazole derivative and salt thereof | TONDE PHARMACEUTICAL CO LTD | 2011-07-20 | — | — | CN | claimed |
| CN-101481353-A | Tetrahydro indazolone or tetrahydro indolone substituted indazole derivative and salt thereof | BEIJING GYLONGLY BIOMEDTECH LT (CN) | 2009-07-15 | — | — | CN | claimed |
| JP-6321922-A | — | — | None | — | — | JP | disclosed |
| US-12030867-B2 | Hsp90β selective inhibitors | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230149295-A1 | INFLAMMATORY BOWEL DISEASE STEM CELLS, AGENTS WHICH TARGET IBD STEM CELLS, AND USES RELATED THERETO | UNIVERSITY OF HOUSTON SYSTEM (US) | 2023-05-18 | — | — | US | disclosed |
| EP-4121111-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY AND FIBROTIC PULMONARY DISORDERS | University of Houston System (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-4117718-A1 | INFLAMMATORY BOWEL DISEASE STEM CELLS, AGENTS WHICH TARGET IBD STEM CELLS, AND USES RELATED THERETO | University of Houston System (US) | 2023-01-18 | — | — | EP | disclosed |
| CN-112315940-B | Nanoparticle for promoting tumor coagulation and enzyme/ATP dual-responsive drug release, and preparation method and application thereof | 暨南大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-1896060-A | Tetrahydro-indolone and tetrahydro-indazolone derivatives and their use | GUOYAO LONGLI BIOLOG MEDICAL N (CN) | 2007-01-17 | — | — | CN | disclosed |
| CN-1896060-A | Tetrahydro-indolone and tetrahydro-indazolone derivatives and their use | GUOYAO LONGLI BIOLOG MEDICAL N (CN) | 2007-01-17 | — | — | CN | disclosed |
| EP-1715921-A2 | TETRAHYDROINDOLONE DERIVATIVES FOR TREATMENT OF NEUROLOGICAL CONDITIONS | Cenomed, Inc. (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005030148-A2 | TETRAHYDROINDOLONE DERIVATIVES FOR TREATMENT OF NEUROLOGICAL CONDITIONS | CENOMED, INC. (US) | 2005-04-07 | — | — | WO | disclosed |
| JP-H06321922-A | HYDRAZINOBENZOTHIAZOLONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1994-11-22 | — | — | JP | disclosed |
| US-4124373-A | Tetrahydroindazole herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-11-07 | — | — | US | disclosed |