Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 13/20 | 0.47 |
| ▸ | FAP | Q12884 | 5/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225901 | 0.92 | CFD (0.46) | CFDFAP | |
| SCHEMBL19225969 | 0.92 | CFD (0.46) | CFDFAP | |
| SCHEMBL19226073 | 0.91 | CFD (0.47) | CFDFAP | |
| SCHEMBL19225904 | 0.91 | CFD (0.47) | CFDFAP | |
| SCHEMBL19225899 | 0.89 | CFD (0.46) | CFDFAPKMT2A | |
| SCHEMBL19225894 | 0.88 | CFD (0.47) | CFDFAPKMT2A | |
| SCHEMBL19226078 | 0.85 | CFD (0.46) | CFDFAP | |
| SCHEMBL19225861 | 0.85 | CFD (0.47) | CFDFAP | |
| SCHEMBL15602024 | 0.85 | CFD (0.47) | CFDFAP | |
| SCHEMBL19226055 | 0.84 | CFD (0.48) | CFDFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |