Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922688 | 1.00 | GCK (0.47) | GCKGPR119 | |
| SCHEMBL1922680 | 0.86 | GCK (0.51) | GCK | |
| SCHEMBL1922682 | 0.86 | GCK (0.51) | GCK | |
| SCHEMBL17273929 | 0.84 | GCK (0.56) | GCK | |
| SCHEMBL17273931 | 0.84 | GCK (0.56) | GCK | |
| SCHEMBL2645861 | 0.78 | GCK (0.50) | GCK | |
| SCHEMBL1924445 | 0.77 | GCK (0.43) | GCK | |
| SCHEMBL2692774 | 0.77 | GCK (0.43) | GCK | |
| SCHEMBL1922674 | 0.77 | GCK (0.59) | GCK | |
| SCHEMBL1922676 | 0.77 | GCK (0.59) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328889-B1 | ACETYL PYRROLIDINYL INDOLE DERIVATIVE | MSD KK (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-8592428-B2 | Acetyl pyrrolidinyl indole derivative | MSD K. K. (JP) | 2013-11-26 | — | — | US | disclosed |
| US-20120108817-A1 | ACETYL PYRROLIDINYL INDOLE DERIVATIVE | MSD K.K. | 2012-05-03 | — | — | US | disclosed |
| EP-2328889-A1 | ACETYL PYRROLIDINYL INDOLE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010018800-A1 | ACETYL PYRROLIDINYL INDOLE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108817-A1 | ACETYL PYRROLIDINYL INDOLE DERIVATIVE | GCKR, GCK, GPR119 | GCK 2/4885GPR119 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.