Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083053 | 0.77 | — | — | |
| SCHEMBL177800 | 0.75 | — | — | |
| SCHEMBL3076740 | 0.74 | — | — | |
| Isobutyramide SCHEMBL3323 | 0.71 | — | — | |
| Isobutyramide SCHEMBL11109750 | 0.71 | LMNA (0.46) | BLMLMNAALOX15PMP22 | |
| SCHEMBL16280519 | 0.71 | LMNA (0.33) | BLMLMNAALOX15PMP22 | |
| SCHEMBL6943656 | 0.71 | — | — | |
| SCHEMBL6944951 | 0.71 | — | — | |
| SCHEMBL14615805 | 0.69 | LMNA (0.38) | BLMLMNAALOX15PMP22 | |
| SCHEMBL28343934 | 0.69 | LMNA (0.32) | BLMLMNAALOX15PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2738190-B1 | AMPHIPHILIC MACROMOLECULE AND USE | BEIJING JUNLUN RUNZHONG SCIENCE&TECHNOLOGY CO LTD (CN) | 2017-08-09 | — | — | EP | disclosed |