Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17210488 | 0.84 | GSR (0.42) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL25288214 | 0.84 | FOLH1 (0.51) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL31321061 | 0.84 | FOLH1 (0.51) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL2628440 | 0.77 | SIRT6 (0.44) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL8291018 | 0.77 | SIRT6 (0.44) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL24642434 | 0.77 | SIRT6 (0.44) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL10442084 | 0.77 | SIRT6 (0.44) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL12649292 | 0.77 | SIRT6 (0.44) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL19647383 | 0.76 | SIRT6 (0.44) | SIRT6SIRT1FOLH1GSRSLC6A5 | |
| SCHEMBL17178883 | 0.76 | SIRT6 (0.41) | SIRT6SIRT1FOLH1GSRSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2720715-B1 | VACCINE COMPOSITION COMPRISING AN INACTIVATED CHIKUNGUNYA VIRUS STRAIN | BHARAT BIOTECH INT LTD (IN) | 2017-08-09 | — | — | EP | disclosed |