SCHEMBL1922792

SCHEMBL1922792

C=CC(=O)C(COC(=O)C(=C)C)OC(=O)C(=C)C

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
THRB P10828 1/20 0.37
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28201554 0.82 TSHR (0.37) TSHRTHRBALDH1A1
SCHEMBL16412067 0.82 TSHR (0.59) TSHRTHRBALDH1A1
SCHEMBL28040899 0.80 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL3199691 0.80 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL10645448 0.80 TSHR (0.49) TSHRTHRBALDH1A1
SCHEMBL2641339 0.78 TSHR (0.46) TSHRTHRBALDH1A1
Ethylene Glycol SCHEMBL10449690 0.77 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL5858947 0.77 TSHR (0.49) TSHRTHRBALDH1A1
SCHEMBL2349030 0.77 TSHR (0.57) TSHRTHRBALDH1A1
SCHEMBL21056351 0.76 TSHR (0.52) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3415912-B1 ANALYTE DETECTION METHOD AND REAGENT KIT FOR DETECTING ANALYTE SYSMEX CORP (JP) 2023-03-29 EP disclosed
US-11169148-B2 Method for detecting test substance and reagent kit for detecting test substance SYSMEX CORPORATION (JP) 2021-11-09 US disclosed
US-10352937-B2 Pretreatment method of sample for detecting HBs antigen and use thereof SYSMEX CORPORATION (JP) 2019-07-16 US disclosed
EP-3444612-A1 IMMUNOASSAY EMPLOYING SULFATED POLYSACCHARIDE LSI Medience Corporation (JP) 2019-02-20 EP disclosed
EP-3415912-A1 ANALYTE DETECTION METHOD AND REAGENT KIT FOR DETECTING ANALYTE Sysmex Corporation (JP) 2018-12-19 EP disclosed
US-20180348212-A1 METHOD FOR DETECTING TEST SUBSTANCE AND REAGENT KIT FOR DETECTING TEST SUBSTANCE SYSMEX CORPORATION (JP) 2018-12-06 US disclosed
EP-2950099-B1 PRETREATMENT METHOD FOR SAMPLE FOR DETECTING HBS ANTIGEN, AND USE THEREFOR SYSMEX CORP (JP) 2018-09-19 EP disclosed
EP-2950099-A1 PRETREATMENT METHOD FOR SAMPLE FOR DETECTING HBS ANTIGEN, AND USE THEREFOR Sysmex Corporation (JP) 2015-12-02 EP disclosed
US-20150330982-A1 PRETREATMENT METHOD OF SAMPLE FOR DETECTING HBS ANTIGEN AND USE THEREOF SYSMEX CORPORATION (JP) 2015-11-19 US disclosed
EP-2327987-B1 Method and kit for detection of HCV core protein SYSMEX CORP (JP) 2013-08-21 EP disclosed
US-20090087926-A1 IMMUNOCHROMATOGRAPHIC TEST DEVICE SYSMEX CORPORATION (JP) 2009-04-02 US disclosed
EP-2042868-A1 Immunochromatographic test device Sysmex Corporation (JP) 2009-04-01 EP disclosed
US-20080268453-A1 Types of lymphoma and method for prognosis thereof AICHI PREFECTURE (JP) 2008-10-30 US disclosed
US-20070184485-A1 Method of diagnosing diseases relating to endometriosis PERIODOCK CO., LTD. (JP) 2007-08-09 US disclosed
US-7241608-B2 Cat kidney disease marker TOHOKU TECHNO ARCH CO., LTD. (JP) 2007-07-10 US disclosed
EP-1676914-A1 DISEASE TYPE OF LYMPHOMA AND METHOD OF ASSESSING PROGNOSIS Aichi Prefecture (JP) 2006-07-05 EP disclosed
US-20060094863-A1 Nucleic acid capable of hybridizing, serving as a marker for diagnosing feline nephropathy YAMASHITA TETSURO 2006-05-04 US disclosed
US-7026151-B2 cats with nephropathy show markedly lowered levels of excretion of a novel protein (named cauxin) with a molecular weight of 70 K, which is excreted into urine in high concentrations in normal adult cats showing no clinical abnormality. TOHOKU TECHNO ARCH CO., LTD. (JP) 2006-04-11 US disclosed
US-20050282177-A1 Types of lymphoma and method for prognosis thereof AICHI PREFECTURE (JP) 2005-12-22 US disclosed
US-20040214171-A1 Cat kidney disease marker TOHOKU TECHNO ARCH CO., LTD. 2004-10-28 US disclosed