Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361963 | 0.87 | TSHR (0.55) | TSHRTHRBALDH1A1 | |
| SCHEMBL8677713 | 0.85 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL28104274 | 0.82 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL29098264 | 0.82 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL2168104 | 0.82 | TSHR (0.59) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL4799744 | 0.82 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL28391183 | 0.81 | TSHR (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL539233 | 0.80 | TSHR (0.61) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11046041 | 0.80 | TSHR (0.61) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL27400837 | 0.80 | TSHR (0.61) | TSHRTHRBALDH1A1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004667-B2 | Organic-inorganic composite filler, and method for producing the same | TOKUYAMA DENTAL CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20170097580-A1 | MEMBER FOR ELECTROPHOTOGRAPHY, DEVELOPING APPARATUS, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2017-04-06 | — | — | US | disclosed |
| EP-2358765-B1 | IMIDIZED POLYMERS CONTAINING LUMINESCENT GROUPS AND METHOD FOR OBTAINING THEM | ENI SPA (IT) | 2016-02-24 | — | — | EP | disclosed |
| US-9187584-B2 | Imidized polymers containing luminescent groups and method for obtaining them | ENI S.P.A. (IT) | 2015-11-17 | — | — | US | disclosed |
| US-20140213687-A1 | ORGANIC-INORGANIC COMPOSITE FILLER, AND METHOD FOR PRODUCING THE SAME | TOKUYAMA DENTAL CORPORATION (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20110301301-A1 | IMIDIZED POLYMERS CONTAINING LUMINESCENT GROUPS AND METHOD FOR OBTAINING THEM | ENI S.P.A. (IT) | 2011-12-08 | — | — | US | disclosed |
| EP-2358765-A1 | IMIDIZED POLYMERS CONTAINING LUMINESCENT GROUPS AND METHOD FOR OBTAINING THEM | ENI S.p.A. (IT) | 2011-08-24 | — | — | EP | disclosed |
| WO-2000047214-A9 | ANTI-RESORPTIVE BONE CEMENTS AND ALLOGENEIC, AUTOGRAFIC, AND XENOGRAFIC BONE GRAFTS | SLOAN KETTERING INST CANCER (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213687-A1 | ORGANIC-INORGANIC COMPOSITE FILLER, AND METHOD FOR PRODUCING THE SAME | CD68, CD44, VCL | TSHR 2462/4885THRB 3627/4885ALDH1A1 1939/4885 |
| US-10004667-B2 | Organic-inorganic composite filler, and method for producing the same | CD68, CD44, VCL | TSHR 2462/4885THRB 3627/4885ALDH1A1 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.