Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 20/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069298 | 0.76 | SLC22A12 (0.67) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL12069331 | 0.76 | SLC22A12 (0.61) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL12069358 | 0.74 | SLC22A12 (0.68) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL14688219 | 0.74 | ALDH1A1 (0.46) | SLC22A12 | |
| SCHEMBL21727908 | 0.73 | SLC22A12 (0.57) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL12070773 | 0.72 | SLC22A12 (0.76) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL12070799 | 0.71 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL12070757 | 0.71 | SLC22A12 (0.83) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL1922914 | 0.71 | SLC22A12 (0.36) | SLC22A12SLC22A11 | |
| SCHEMBL15159018 | 0.70 | SLC22A12 (0.77) | SLC22A12SLC22A6SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328874-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF USING SAME FOR MODULATING URIC ACID LEVELS | Ardea Biosciences, Inc. (US) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010028189-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF USING SAME FOR MODULATING URIC ACID LEVELS | ARDEA BIOSCIENCES, INC. (US) | 2010-03-11 | — | — | WO | disclosed |