Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255681 | 0.81 | RIPK1 (0.48) | RIPK1 | |
| SCHEMBL30449921 | 0.81 | RIPK1 (0.48) | RIPK1 | |
| SCHEMBL19224567 | 0.81 | RIPK1 (0.48) | RIPK1 | |
| Hydrochloric Acid SCHEMBL31663493 | 0.80 | RIPK1 (0.47) | RIPK1 | |
| Hydrochloric Acid SCHEMBL29415740 | 0.80 | RIPK1 (0.47) | RIPK1 | |
| Hydrochloric Acid SCHEMBL19207511 | 0.80 | RIPK1 (0.47) | RIPK1 | |
| Hydrochloric Acid SCHEMBL19207536 | 0.80 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL30336156 | 0.78 | CYP11B1 (0.47) | RIPK1 | |
| SCHEMBL4067526 | 0.78 | CYP11B1 (0.47) | RIPK1 | |
| SCHEMBL31025716 | 0.77 | CHRNB4 (0.36) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815850-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170226127-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226127-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | PIK3CA, PLK1, PIK3CB | RIPK1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.