Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.78 |
| ▸ | CRYAB | P02511 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | FNTA | P49354 | 1/20 | 0.67 |
| ▸ | FNTB | P49356 | 1/20 | 0.67 |
| ▸ | PTGES | O14684 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 1/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.55 |
| ▸ | CRYAA | P02489 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192284 | 1.00 | MAPT (0.78) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4738414 | 0.88 | MAPT (0.82) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL19194140 | 0.88 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL415761 | 0.88 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL17431708 | 0.88 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL415760 | 0.88 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL6130526 | 0.88 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2340127 | 0.88 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5666302 | 0.88 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4737573 | 0.88 | MAPT (0.80) | MAPTUSP2ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175553-A1 | LOW RESISTANCE AEROSOL EXHALATION FILTER | INSMED INCORPORATED | 2016-06-23 | — | — | US | claimed |
| EP-3021920-A1 | LOW RESISTANCE AEROSOL EXHALATION FILTER | Insmed Incorporated (US) | 2016-05-25 | — | — | EP | claimed |
| EP-2853264-A1 | Nanodispersion | Sun Pharma Advanced Research Company Limited (IN) | 2015-04-01 | — | — | EP | claimed |
| US-20150020802-A1 | LOW RESISTANCE AEROSOL EXHALATION FILTER | INSMED INCORPORATED (US) | 2015-01-22 | — | — | US | claimed |
| WO-2015009920-A1 | LOW RESISTANCE AEROSOL EXHALATION FILTER | INSMED INCORPORATED (US) | 2015-01-22 | — | — | WO | claimed |
| US-20080131497-A1 | Formulations of DNase and Methods of Use Thereof | TRANSAVE, INC. | 2008-06-05 | — | — | US | claimed |
| US-20080107723-A1 | Methods of Treating Pulmonary Distress | TRANSAVE, INC. | 2008-05-08 | — | — | US | claimed |
| WO-2008039987-A2 | METHODS OF TREATING PULMONARY DISTRESS | TRANSAVE, INC. (US) | 2008-04-03 | — | — | WO | claimed |
| WO-2008039989-A2 | FORMULATIONS OF DNASE AND METHODS OF USE THEREOF | TRANSAVE, INC. (US) | 2008-04-03 | — | — | WO | claimed |
| EP-4393491-A2 | METHODS FOR TREATING PULMONARY NON-TUBERCULOUS MYCOBACTERIAL INFECTIONS | Insmed Incorporated (US) | 2024-07-03 | — | — | EP | disclosed |
| US-12016873-B2 | Methods for treating pulmonary non-tuberculous mycobacterial infections | INSMED INCORPORATED (US) | 2024-06-25 | — | — | US | disclosed |
| CN-118141701-A | Composition containing benzoic acid derivative or furoic acid derivative and use of the derivative for emulsion and foam stability | 西姆莱斯股份公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118159632-A | Perfume and perfume mixture | 西姆莱斯股份公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-4351730-A1 | IN VITRO RELEASE ASSAY METHODS FOR LIPOSOMAL AMINOGLYCOSIDE FORMULATIONS | Insmed Incorporated (US) | 2024-04-17 | — | — | EP | disclosed |
| US-20030078196-A1 | Treatment of cancers by inhalation of stable platinum-containing formulations | TRANSAVE, INC. (US) | 2003-04-24 | — | — | US | disclosed |
| US-20030059375-A1 | Method for treating lung cancers | TRANSAVE, INC. | 2003-03-27 | — | — | US | disclosed |
| WO-2003015521-A1 | TREATMENT OF CANCERS BY INHALATION OF STABLE PLATINUM-CONTAINING FORMULATIONS | TRANSAVE, INC. (US) | 2003-02-27 | — | — | WO | disclosed |
| WO-2003015707-A2 | METHOD FOR TREATING LUNG CANCERS | TRANSAVE, INC. (US) | 2003-02-27 | — | — | WO | disclosed |
| EP-1128813-A1 | AN INHALATION SYSTEM | Pilkiewicz, Frank G. (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027359-A1 | AN INHALATION SYSTEM | PILKIEWICZ FRANK G (US) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080107723-A1 | Methods of Treating Pulmonary Distress | LIPA, CFTR, ELANE | MAPT 4813/4885USP2 300/4885ALDH1A1 3726/4885 |
| US-20080131497-A1 | Formulations of DNase and Methods of Use Thereof | DNASE1, DNASE1L3, ELANE | MAPT 4481/4885USP2 463/4885ALDH1A1 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.