Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | YES1 | P07947 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230314 | 0.91 | TTR (0.59) | ARCYP3A4TTRCYP19A1PTGS1 | |
| SCHEMBL4360585 | 0.86 | AR (0.64) | ARCYP3A4TTRCYP19A1PTGS1 | |
| SCHEMBL4366665 | 0.82 | AR (0.76) | ARCYP3A4TTRCYP19A1TUBB4A | |
| SCHEMBL4374168 | 0.80 | AR (0.73) | ARCYP3A4PBRM1TTRCYP19A1 | |
| SCHEMBL19230285 | 0.79 | ESR2 (0.57) | ARTTRCYP19A1PTGS1PTGS2 | |
| SCHEMBL1825322 | 0.77 | AR (0.58) | ARCYP3A4PBRM1CYP19A1MAOA | |
| SCHEMBL1823377 | 0.76 | AR (0.57) | ARCYP3A4PBRM1CYP19A1TUBB4A | |
| SCHEMBL26125489 | 0.76 | CYP19A1 (0.81) | CYP3A4TTRCYP19A1PTGS1PTGS2 | |
| SCHEMBL11249386 | 0.76 | PBRM1 (0.63) | ARCYP3A4PBRM1CYP19A1TUBB4A | |
| SCHEMBL1821563 | 0.75 | AR (0.66) | ARCYP3A4PBRM1CYP19A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |