Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.57 |
| ▸ | ESR1 | P03372 | 9/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230670 | 0.90 | ESR2 (0.53) | ESR2ESR1 | |
| SCHEMBL4366876 | 0.85 | ESR2 (0.61) | ESR2ESR1ARTTRPTGS1 | |
| SCHEMBL19230545 | 0.81 | ESR1 (0.53) | ESR2ESR1TTRCYP19A1 | |
| SCHEMBL28649906 | 0.81 | ESR1 (0.53) | ESR2ESR1ARTTRPDK1 | |
| SCHEMBL19230953 | 0.81 | ESR2 (0.50) | ESR2ESR1ARPDK1PDK2 | |
| SCHEMBL4371924 | 0.81 | ESR2 (0.62) | ESR2ESR1ARTTRCYP19A1 | |
| SCHEMBL4368187 | 0.79 | ESR2 (0.68) | ESR2ESR1ARCYP19A1 | |
| SCHEMBL19230284 | 0.79 | AR (0.66) | ESR2ARTTRPTGS1PTGS2 | |
| SCHEMBL19230656 | 0.78 | ESR1 (0.49) | ESR2ESR1PDK1PDK2PDK3 | |
| SCHEMBL19230805 | 0.78 | ESR1 (0.49) | ESR2ESR1PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |