Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.46 |
| ▸ | BRD4 | O60885 | 7/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BMX | P51813 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105874 | 0.82 | BTK (0.54) | BTKEGFRBMXJAK3 | |
| SCHEMBL1322596 | 0.73 | BTK (0.73) | BTKBMX | |
| SCHEMBL20578298 | 0.73 | BTK (0.59) | BTKEGFRBMXJAK3 | |
| SCHEMBL20578299 | 0.72 | BTK (0.56) | BTKEGFRBMXJAK3 | |
| SCHEMBL20578293 | 0.71 | BTK (0.59) | BTKEGFRBMXJAK3 | |
| SCHEMBL20578196 | 0.70 | BTK (0.65) | BTKEGFRBMXJAK3 | |
| SCHEMBL20578265 | 0.69 | BTK (0.57) | BTKEGFRBMXJAK3 | |
| SCHEMBL12956109 | 0.69 | BTK (0.59) | BTKEGFRBMXJAK3 | |
| SCHEMBL20716894 | 0.67 | BTK (0.54) | BTK | |
| SCHEMBL13044230 | 0.67 | BTK (0.59) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133341-A1 | NOVEL IRREVERSIBLE BRUTON'S TYROSINE KINASE INHIBITOR | 中国科学院合肥物质科学研究院 | 2017-08-10 | — | — | WO | disclosed |