SCHEMBL19230417

SCHEMBL19230417

O=C1C(=O)c2cc3ccccc3cc2-c2cc3ccccc3cc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HPGD P15428 3/20 0.52
MAPK1 P28482 2/20 0.52
TP53 P04637 2/20 0.52
CASP1 P29466 2/20 0.52
CASP7 P55210 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TSHR P16473 1/20 0.52
HIF1A Q16665 1/20 0.52
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
PTPRC P08575 4/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
LMNA P02545 4/20 0.50
HTT P42858 4/20 0.50
CES1 P23141 3/20 0.50
S100A4 P26447 3/20 0.50
APAF1 O14727 3/20 0.50
GALK1 P51570 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30458681 0.94 MEN1 (0.53) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL16144676 0.94 MEN1 (0.53) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL29634145 0.94 MEN1 (0.53) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL2198881 0.92 PTPRC (0.65) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL29364188 0.91 MEN1 (0.56) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL354514 0.91 MEN1 (0.56) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL30130196 0.91 MEN1 (0.56) ALDH1A1HPGDMAPK1TP53CASP1
Ammonia Solution, Strong SCHEMBL28255083 0.88 MEN1 (0.53) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL5145444 0.88 PTPRC (0.59) ALDH1A1HPGDMAPK1TP53CASP1
SCHEMBL347152 0.87 MEN1 (0.60) ALDH1A1HPGDMAPK1TP53CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190048129-A1 A POLYMER, COMPOSITION, FORMING SACRIFICIAL LAYER AND METHOD FOR SEMICONDUCTOR DEVICE THEREWITH AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2019-02-14 US disclosed
WO-2017137142-A1 A POLYMER, COMPOSITION, FORMING SACRIFICIAL LAYER AND METHOD FOR SEMICONDUCTOR DEVICE THEREWITH AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2017-08-17 WO disclosed