Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230491 | 1.00 | MAPK1 (0.41) | MAPK1GRNSORT1 | |
| SCHEMBL13711068 | 0.86 | MAPK1 (0.40) | MAPK1GRNSORT1 | |
| SCHEMBL13711120 | 0.86 | MAPK1 (0.40) | MAPK1GRNSORT1 | |
| SCHEMBL1693987 | 0.83 | GRN (0.50) | MAPK1GRNSORT1 | |
| SCHEMBL1693084 | 0.83 | GRN (0.50) | MAPK1GRNSORT1 | |
| SCHEMBL28528204 | 0.83 | MAPK1 (0.41) | MAPK1GRNSORT1 | |
| SCHEMBL5048325 | 0.83 | GRN (0.50) | MAPK1GRNSORT1 | |
| SCHEMBL1361481 | 0.83 | MAPK1 (0.41) | MAPK1GRNSORT1 | |
| Hydrochloric Acid SCHEMBL2490304 | 0.82 | GRN (0.49) | MAPK1GRNSORT1 | |
| SCHEMBL12661117 | 0.79 | GRN (0.40) | MAPK1GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136708-A1 | SYNTHESIS AND COMPOSITION OF RAPAFUCIN LIBRARIES | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-10 | — | — | WO | disclosed |